BDBM140382 US10947243, Example 107::US8912173, 107::US9914735, Example 107

SMILES C[C@@H](Oc1cc(cc2ncccc12)-c1ccc2nc(C)nc(C)c2c1)[C@H]1CNC(=O)C1

InChI Key InChIKey=HYXFMJAJQAKJSH-DNVCBOLYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140382   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140382(US10947243, Example 107 | US8912173, 107 | US99147...)
Affinity DataIC50:  4.90nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140382(US10947243, Example 107 | US8912173, 107 | US99147...)
Affinity DataIC50:  9nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) ...More data for this Ligand-Target Pair
In DepthDetails US Patent